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Herbal combination tames active UC in small study
Derivatives of an intensely yellow spice and an intensely blue dye combined to resolve active ulcerative colitis in a small randomized trial.
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Adult stem cells can heal intractable perianal Crohn’s fistulae
Many patients experienced complete healing within 3 months of a single infusion of mesenchymal stem cells.
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Gut enzymes fingered in some 5-ASA treatment failures
Patients with inflammatory bowel disease who had three or four specific acetyltransferases in their gut microbiota had a threefold higher risk for...
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Food additives may exacerbate IBD
Emulsifiers and thickeners added to food in processing may contribute to inflammation and changes in gut microbiota.
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Proof lacking for dual-targeted therapy benefit in IBD
Questions remain unanswered about the effectiveness of combination biologic treatment for inflammatory bowel disease.
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Four-gene signature linked to increased PML risk
Investigators have identified four immune-associated genes that put immunocompromised patients at risk for progressive multifocal...
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Capivasertib/fulvestrant improves progression free survival in breast cancer
The combination of the investigational AKT inhibitor capivasertib and estrogen receptor antagonist fulvestrant, doubled progression-free survival...
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Steep cost of surviving childhood HL: Epigenetic aging
New research found accelerated epigenetic aging in most adults who survived pediatric Hodgkin lymphoma.
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Alloantibody registry would save lives, money
New research supports establishing a national exchange of alloantibody data, to save lives and cut costs in transfusion medicine.
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Gene signature may spare some breast cancer patients from radiation
The POLAR 16-gene mRNA signature accurately identified patients who were unlikely to benefit from radiotherapy after breast-conserving surgery.
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‘Exciting’ responsiveness to talquetamab for r/r MM
The novel antibody talquetamab may buy time for patients with multiple myeloma (MM) for whom few other options remain.
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Pricey gene therapy looks cost-effective for SCD
Researchers calculated that a costly new treatment being developed for sickle cell disease (SCD) promises to be worth the price.
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A bold national plan to eliminate HCV by 2050
“We don’t get to use the ‘eliminate’ word all that often with a disease that’s taking thousands or tens of thousands – or worldwide, hundreds of...
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High response rates with T-DXd in early HER2-low breast cancer
Nearly 70% of patients with hormone receptor-positive breast cancers with low levels of HER2 had pathological response to the antibody-drug...
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‘Clear answer’: ALL study defies conventional wisdom
Research on pediatric blood cancers found that high-dose methotrexate does not help cut the risk for central nervous system relapse.