Clinical Edge Journal Scan

Detrimental impact of atopic dermatitis on families of pediatric patients


 

Key clinical point: Atopic dermatitis (AD) had a detrimental impact on the families of pediatric patients, with not only severe AD but even mild AD having a substantial impact on family life.

Major finding: There was a substantial impact of AD on families across geographic regions, as assessed by Dermatitis Family Impact (DFI) score, which increased with the severity of AD (mild: 3.3-11.3, moderate: 6.9-17.1, and severe: 11-20.3). A DFI score of >9.6 was reported for 37.2%, 70.7%, and 78.0% of patients with mild, moderate, and severe AD, respectively.

Study details: Findings are from the cross-sectional, web-based survey including 7465 pairs of pediatric patients with AD and their parents/caregivers.

Disclosures: This study was funded by Sanofi and Regeneron Pharmaceuticals Inc. Five authors declared being current or former employees or stockholders of Sanofi or Regeneron Pharmaceuticals, and some others declared ties with various sources.

Source: Barbarot S et al. The family impact of atopic dermatitis in the pediatric population: Results from an international cross-sectional study. J Pediatr. 2022 (Apr 28). Doi: 10.1016/j.jpeds.2022.04.027

Recommended Reading

Steroid phobia drives weaker prescribing, nonadherence for AD
MDedge Dermatology
Moderate-to-severe atopic dermatitis: Abrocitinib shows promise in patients who switch from dupilumab
MDedge Dermatology
Atopic dermatitis: Higher threshold efficacy response and QoL benefits with abrocitinib
MDedge Dermatology
Atopic dermatitis: Baricitinib+TCS shows promise in patients with inadequate response to CyA
MDedge Dermatology
Atopic dermatitis: Dupilumab shows potential as a long-term, continuous treatment option
MDedge Dermatology
Higher sensitivity to contact allergens in children with atopic dermatitis
MDedge Dermatology
Nemolizumab safe and efficacious in relieving pruritus and reducing severity of atopic dermatitis
MDedge Dermatology
Dupilumab beneficial for adolescents with moderate-to-severe atopic dermatitis in the real world
MDedge Dermatology
Meta-analysis highlights favorable efficacy and safety of antioxidants in atopic dermatitis
MDedge Dermatology
Children with atopic dermatitis prone to develop proinflammatory dietary pattern
MDedge Dermatology