Clinical Edge | MDedge Family Medicine

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

This Week's Must Reads

Younger adults present with more advanced esophageal adenocarcinoma,

Osteoporosis prevalence in PsA similar to general population,

Annual WCC visits significantly limit asthma worsening,

U.S. mothers underestimate role breastfeeding plays in curbing breast cancer,

Microplastics permeate human placentas,

Clinical Guidelines

USPSTF: Interventions to Avert Perinatal Depression, JAMA; 2019 Feb 12; US Preventive Services Task Force

ACIP Updates Adult Immunization Schedule, Ann Intern Med; 2019 Feb 5; Kim, Hunter, et al

Read more in Clinical Guidelines

FDA Actions

FDA Approves Steglatro for Adults with T2D, Pfizer news release; 2017 Dec 22

FDA Approves Ozempic for Treatment of T2D, Novo Nordisk news release; 2017 Dec 5

Read more in FDA Actions

Sleep Medicine

Study links sleep meds and dementia risk in older adults,

Sleep apnea may correlate with anxiety, depression in patients with PCOS,

Read more in Sleep Medicine

Rheumatology

Osteoporosis prevalence in PsA similar to general population,

Weight loss may be paramount lifestyle change in preventing gout,

Read more in Rheumatology

Vaccines

COVID-19–induced drop in first measles vaccinations sparks resurgence concerns,

Vaccine-preventable infection risk high for pediatric hematopoietic cell transplantation recipients,

Read more in Vaccines

Sleep Medicine

Study links sleep meds and dementia risk in older adults,

Sleep apnea may correlate with anxiety, depression in patients with PCOS,

Read more in Sleep Medicine

Preventive Care

Sedentary postmenopausal women have higher heart failure risk,

Don’t miss cardiovascular risk factors in transgender patients,

Read more in Preventive Care

Pediatrics

Annual WCC visits significantly limit asthma worsening,

Does daily inhaler monitoring improve asthma outcomes in children?,

Read more in Pediatrics

Practice Management

Health disparities training falls short for internal medicine residents,

Men occupy most leadership roles in medicine,

Read more in Practice Management

Mixed Topics

Swedish registry study finds atopic dermatitis significantly associated with autoimmune diseases,

Fecal transplant linked to reduced C. difficile mortality,

Read more in Mixed Topics

Pulmonology

Does daily inhaler monitoring improve asthma outcomes in children?,

COVID-19–induced drop in first measles vaccinations sparks resurgence concerns,

Read more in Pulmonology

Rare Diseases

Esophageal stricture signals urgent treatment in kids with butterfly skin,

Deferiprone noninferior to deferoxamine for iron overload in SCD, rare anemias,

Read more in Rare Diseases

Heartburn/Acid Reflux

PPIs associated with diabetes risk, but questions remain,

GERD: Endoscopic therapies may offer alternative to PPIs,

Read more in Heartburn/Acid Reflux

COVID-19 Updates

Anorexia and diarrhea top list of GI symptoms in COVID-19 patients,

COVID-19 vaccine found effective but doctors watching for reactions, adverse events,

Read more in COVID-19 Updates

Colorectal Cancer

Geography and behaviors linked to early-onset colorectal cancer survival in U.S. women,

Statins may lower risk of colorectal cancer,

Read more in Colorectal Cancer

Transgender Health

Gender surgical outcomes differ following puberty suppression,

Don’t miss cardiovascular risk factors in transgender patients,

Read more in Transgender Health

All Specialties