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Outcomes in Lymphoblastic Lymphoma Patients Evaluated

Clin Lymphoma Myeloma Leuk; ePub 2017 Jun 6; El-Fattah

Adults with lymphoblastic lymphoma (LL) experienced poor long-term outcomes in an analysis involving nearly 700 individuals. Participants all had LL that was recorded between 2001 to 2012. Investigators looked at clinical prognostic factors, stratified by histologic subtypes. Among the results:

  • 53% of patients had T-LL, and 19% had B-LL.
  • Patients with T-LL tended to be younger (33 years vs. 48 years) and male (66% vs. 50%).
  • They were less likely to have an extra-nodal involvement (6% vs. 32%).
  • 5-year survival rates of B-LL (45%) and T-LL (48%) were similar even after adjustment for certain variables.
  • Age, race, and radiotherapy were independent prognostic factors T-LL outcome.
  • Limited tumor stage and the most recent year of diagnosis were favorable prognostic factors for B-LL.

Citation:

El-Fattah M. Prognostic factors and outcomes of adult lymphoblastic lymphoma in the United States. [Published online ahead of print June 6, 2017]. Clin Lymphoma Myeloma Leuk. doi:10.1016/j.clml.2017.05.016.