Facilities that treat more cases of mycosis fungoides and Sézary syndrome (MF/SS) offer patients with these disorders improved survival, according to a study involving more than 2,200 individuals.

Participants who were diagnosed with MF/SS between 2004 and 2011 at 374 facilities were grouped into quintiles according to their facility’s average annual treatment volume (ATV). ATV quintile cutoffs were 1, 3, 6, and 9 patients. Investigators looked at overall survival both between quintiles and using annual patient volume as a continuous variable. Among the results:

• After a median follow-up of 59 months, 5-year estimated overall survival increased with ATV from 57% in the lowest quintile to 84% in the highest.
• Higher ATV was linked with improved survival when analyzed as a continuous variable or when comparing the highest quintile to the lowest quintile.