Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions
Lifestyle choices may reduce breast cancer risk regardless of genetics
Key clinical point: Certain lifestyle choices may reduce the likelihood of breast cancer regardless of genetic risk factors.
Major finding: When compared with women who had a “favorable” lifestyle, those with an “unfavorable” lifestyle had a higher risk of breast cancer whether they had low genetic risk (hazard ratio, 1.63), intermediate genetic risk (HR, 1.94), or high genetic risk (HR, 1.39).
Study details: Analysis of data on 91,217 women in the UK Biobank.
Disclosures: This research was funded by the National Institute for Health Research Manchester Biomedical Research Centre, the Alan Turing Institute, and a Cancer Research UK Integrated Cancer Epidemiology Programme grant. The investigators had no relevant disclosures.
Al Ajmi K et al. JAMA Netw Open. 2020;3(4):e203760.