Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Atezolizumab/bevacizumab may offer benefit to patients with RCC

Key clinical point: Atezolizumab plus bevacizumab may be useful in patients with advanced renal cell carcinoma who are PD-L1–positive.

Major finding: The overall response rate among such patients was 60% compared with 19% in PD-L1–negative patients.

Study details: The open-label study comprised 60 patients.

Disclosures: Bristol-Myers Squibb sponsored the study. Dr. McGregor reporter consultancy roles for Bayer AG, Seattle Genetics, Astellas Pharma, Exelixis, AstraZeneca, Genentech, Roche, Nextar, Janssen Oncology, Pfizer, EMD Serono Research.

Citation:

McGregor BA et al. J Clin Oncol. 2019 Nov 13. doi: 10.1200/JCO.19.01882.