Clinical Edge

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Study simplifies bladder cancer molecular subtypes

Key clinical point: Muscle-invasive bladder cancer can be divided into six molecular classes that may guide prognosis and treatment planning.

Major finding: Neuroendocrine-like muscle-invasive bladder cancer tumors were associated with the poorest outcome (hazard ratio, 2.34; P less than .03).

Study details: A group consensus based on a retrospective meta-analysis involving 1,750 transcriptomic profiles.

Disclosures: The investigators reported relationships with Bayer, Astellas, Genentech, and others.

Citation:

Kamoun A et al. Eur Urol. 2019 Sep 26. doi: 10.1016/j.eururo.2019.09.006.