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Transdiagnostic Disorders Linked with Early Menarche

Compr Psychiatry; ePub 2017 Jul 6; Platt, Colich, et al

Earlier age of pubertal maturation in females is associated with increased risk for mental health problems in adolescence, compared with on-time or later maturation, according to existing research. A recent study, however, illuminated meaningful transdiagnostic psychiatric associations with early timing of menarche. Data on age of menarche and mental disorders were drawn from a population-representative sample of adolescents (n= 4,925), aged 13–17 years. Confirmatory factor analysis was used to fit 4 latent disorder categories: distress, eating, and externalizing, and fear disorders. Timing of menarche included those with earlier (age ≤10, age 11) and later age of onset (age 13, 14+), relative to those with average timing of menarche (age 12). Researchers found:

  • Onset of menarche before age 11 was significantly associated with distress disorders, fear disorders, and externalizing disorders as compared to on-time or late menarche.
  • No residual associations of early menarche with individual disorders over and above the latent disorders were observed.

Citation:

Platt J, Colich NL, McLaughlin KA, Gary D, Keyes KM. Transdiagnostic psychiatric disorder risk associated with early age of menarche: A latent modeling approach. [Published online ahead of print July 6, 2017]. Compr Psychiatry. doi:10.1016/j.comppsych.2017.06.010.