Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Cognitive Behavioral Therapy for Insomnia

Can CBT-I help patients with psychiatric conditions?

Publish date:: July 16, 2015

Insomnia symptoms and sleep parameters for patients with comorbid (CBT) insomnia can be improved with cognitive behavioral therapy, according to a meta-analysis of 37 studies that also examined the relationship to psychiatric and medical conditions. Researchers found:

• A small to medium positive effect was found across comorbid outcomes using CBT-I.

• Larger effects were on psychiatric conditions compared with medical conditions.

• 36% of patients who received CBT-I were in remission from insomnia at post-treatment evaluation compared with 16.9% in comparison conditions.

Citation: Wu JQ, Appleman ER, Salazar RD, Ong JC. Cognitive behavioral therapy for insomnia comorbid with psychiatric and medical conditions: A meta-analysis. JAMA Intern Med. [Published online before print July 6, 2015]. doi:10.1001/jamainternmed.2015.3006.

This Week's Must Reads

MDD: Modest improvements in female sexual functioning with adjunctive brexpiprazole,

Transcranial direct current stimulation not clinically relevant in MDD,

Interleukin-1 β and TNF-α hamper antidepressant response in MDD,

Impact of pimavanserin on anxious depression in patients with MDD,

Prior MDD moderates the association between endothelin-1 and post-ACS depressive symptoms,

Must Reads in Sleep Medicine

Study links sleep meds and dementia risk in older adults,

Study validates OSA phenotypes in Latinos,

Insomnia may have a role in generation of stressful life events,

Study confirms link between PAP apnea treatment and dementia onset,

Sleep EEG may predict later antidepressant response,