Key clinical point: Oral beta-blockers may be helpful in treating facial erythema and flushing in rosacea, but more data are needed.

Major finding: Carvedilol and propranolol showed a large reduction of symptoms.

Study design: A systematic review of nine studies that evaluated beta-blockers for facial erythema and flushing.

Disclosures: Jade G.M. Logger, MD, disclosed financial relationships with Galderma, AbbVie, Novartis, Janssen, and LEO Pharma; one author disclosed conducting clinical trials for AbbVie and Novartis; the third author disclosed relationships with Galderma, Cutanea Life Sciences, AbbVie, Novartis, and Janssen, with fees paid to his institution.