Clinical Edge

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Postcolonoscopy antibiotics linked with IBS

Key clinical point: Antibiotic exposure within 14 days after screening colonoscopy may increase risk of irritable bowel syndrome.

Major finding: Individuals exposed to antibiotics within 14 days after screening colonoscopy had a 77% increased risk of developing irritable bowel syndrome (adjusted odds ratio, 1.77; 95% CI, 1.31-2.39).

Study details: A retrospective cohort study involving 402,259 individuals who underwent screening colonoscopy.

Disclosures: The investigators disclosed relationships with Merck, Pfizer, Gilead, and others.

Citation:

Vajravelu R et al. DDW 2020. Abstract 404.