Clinical Inquiries
Clinical Inquiries
What are the benefits and risks of daily low-dose aspirin for primary prevention of CV events?
EVIDENCE-BASED ANSWER: One nonfatal myocardial infarction (MI) will be avoided for every 126 to 138 adults who take daily aspirin for 10 years (...
Clinical Inquiries
Does exercise relieve vasomotor menopausal symptoms?
EVIDENCE-BASED ANSWER: No. Exercise doesn’t decrease the frequency or severity of vasomotor menopausal symptoms (VMS) in perimenopausal and...
Clinical Inquiries
Is megestrol acetate safe and effective for malnourished nursing home residents?
EVIDENCE-BASED ANSWER: No. Megestrol acetate (MA) is neither safe nor effective for stimulating appetite in malnourished nursing home residents....
Clinical Inquiries
How do oral NSAIDs compare to other oral analgesics right after an acute musculoskeletal injury?
EVIDENCE-BASED ANSWER: Nonsteroidal anti-inflammatory drugs (NSAIDs) are at least as effective as other oral analgesics (opioids, acetaminophen)...
Clinical Inquiries
How do hyaluronic acid and corticosteroid injections compare for knee OA relief?
EVIDENCE-BASED ANSWER: Inconsistent evidence shows a small amount of pain relief early (one week to 3 months) with corticosteroid (CS) injections...
Clinical Inquiries
Which interventions are effective in managing parental vaccine refusal?
EVIDENCE-BASED ANSWER: It’s unclear whether educational initiatives alone alter vaccine refusal. Although about a third of parents cite herd...
Clinical Inquiries
What is the optimal frequency for dental checkups for children and adults?
EVIDENCE-BASED ANSWER: It is unclear, but studies suggest that it should be based largely on individual risk. The American Academy of Pediatric...
Clinical Inquiries
Are oral emergency contraceptives a safe & effective form of long-term birth control?
EVIDENCE-BASED ANSWER: Yes, but not as effective as some other methods. Annual pregnancy rates in women using pericoital levonorgestrel 150 mcg to...
Clinical Inquiries
What is the most effective treatment for scabies?
Topical permethrin is the most effective treatment for classic scabies, but oral ivermectin may reduce . . .
Clinical Inquiries
What effects—if any—does marijuana use during pregnancy have on the fetus or child?
EVIDENCE-BASED ANSWER: The effects are unclear. Marijuana use during pregnancy is associated with clinically unimportant lower...
Clinical Inquiries
Do oral decongestants have a clinically significant effect on BP in patients with hypertension?
EVIDENCE-BASED ANSWER: It is unclear. Pseudoephedrine causes an average increase of 1.2 mm Hg in systolic blood pressure (BP) in...