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Exercise intolerance linked to neurocognitive dysfunction in ALL

Publish date:: October 22, 2019

Key clinical point: Exercise intolerance was associated with worse neurocognitive function in adult survivors of pediatric acute lymphoblastic leukemia.

Major finding: Acute lymphoblastic leukemia survivors had lower mean relative peak volume of oxygen scores and worse performance on several neurocognitive measures, compared with controls (all P less than .001).

Study details: A cross-sectional cohort study of 341 adult survivors of pediatric acute lymphoblastic leukemia and 288 healthy controls.

Disclosures: The study was supported by the National Institutes of Health and the American Lebanese Syrian Associated Charities. The researchers did not report conflicts of interest.

Citation:

Phillips NS et al. Cancer. 2019 Oct 21. doi: 10.1002/cncr.32510.

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