Leukemia, Myelodysplasia, Transplantation
News
Mutant B-cell progenitor causes leukemia, group finds
Credit: Aaron Logan Researchers have identified a cell that appears to be responsible for a particularly aggressive type of leukemia in mice....
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Early dasatinib response predicted long-term survival in imatinib-resistant chronic phase chronic myeloid leukemia
Major finding: At 6 years of follow-up, patients receiving 100 mg dasatinib daily had an overall survival of 71% and progression-free survival of...
Conference Coverage
RIT can improve transplant outcomes in NHL, CLL
Ryan Cassaday, MD, of the University of Washington in Seattle, noted that RIT-augmented NMAT can produce long-term remissions in patients with...
News
Pathway may drive treatment resistance in T-ALL
Experiments in zebrafish have revealed a mechanism that may drive relapse in human T-cell acute lymphoblastic leukemia (T-ALL). Researchers...
News
England’s Cancer Drugs Fund raises concerns
Credit: Rhoda Baer Cancer patients in England are more likely to receive prescriptions for expensive drugs than patients in Wales, according to a...
Conference Coverage
Study links graft source to length of hospital stay
The study also suggests the length of stay (LOS) is similar whether patients receive double or single CB grafts. So it seems strategies are...
Conference Coverage
CNS involvement doesn’t affect survival after allo-SCT
By analyzing transplant outcomes in more than 5000 patients, researchers found that subjects with CNS AML had rates of relapse and survival that...
News
Palliative chemo can have undesired outcomes
Credit: Rhoda Baer Palliative chemotherapy can negatively impact the end of life for terminally ill cancer patients, according to a paper...
News
Drugs get orphan designation for AML, MM
Credit: FDA The US Food and Drug Administration (FDA) has granted orphan designation for the histone deacetylase (HDAC) inhibitor pracinostat to...
News
Targeting pathways can override resistance in ALL
Inhibiting two biosynthesis pathways can override treatment resistance in acute lymphoblastic leukemia (ALL), preclinical research suggests....
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How Bcl-2 helps cancer cells survive treatment
Researchers believe they’ve discovered how the Bcl-2 protein helps leukemia and lymphoma cells survive anticancer treatment. The team found that...