Leukemia, Myelodysplasia, Transplantation
News
FDA expands ibrutinib approval to include chronic lymphocytic leukemia
News
Normal enzyme aids mutated FLT3 to fuel AML
Results of preclinical research suggest the wild-type version of SYK pairs with mutated FLT3 to promote progression of acute myelogenous leukemia...
News
Improving the efficacy of etoposide
after treatment with etoposide Credit: CNIO A compound that interferes with the cell cycle can increase the antineoplastic effects of etoposide,...
News
Power lines don’t raise leukemia risk in kids
An earlier study using information on childhood leukemia diagnosed between 1962 and 1995 suggested there was an elevated risk for children born...
News
Sequencing reveals therapeutic target for leukemias
of General Medical Sciences By analyzing the whole genomes of 3-year-old twin sisters—one healthy and one with multi-lineage leukemia (MLL)—...
News
Combo may overcome drug resistance in ALL
Credit: Linda Bartlett Adding the alkylating agent cyclophosphamide to treatment with a monoclonal antibody (mAb) can overcome drug resistance in...
News
Affluence seems to affect CML survival in the UK
Credit: CDC Results of population-based research suggest that financial status may affect survival in patients with chronic myeloid leukemia (CML...
News
FDA approves system for GVHD prophylaxis
Credit: Miltenyi Biotec The US Food and Drug Administration (FDA) has granted approval for a device system that can prevent graft-vs-host disease...
News
Methylation patterns can predict survival in AML, team says
Credit: Lance Liotta Researchers have found evidence to suggest that methylation patterns in hematopoietic stem cells (HSCs) can be used to...
News
Protein ‘critical’ for function of HSCs, LSCs
(endoplasmic reticulum in green, mitochondria in red, and chromosomes in blue) Wellcome Images The dynein-binding protein Lis1 is critical for...
News
Mouse model provides new insight into AML
Studies have suggested that mutations in isocitrate dehydrogenase-1 and 2 (IDH1 and IDH2) are present in approximately 20% of all acute myeloid...