Leukemia, Myelodysplasia, Transplantation
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Physical activity may cut death risk in male cancer survivors
Credit: Jason E.
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Ibrutinib trial stopped early
Credit: Steven Harbour The phase 3 RESONATE study has been stopped early due to positive results in patients receiving ibrutinib. In this trial...
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Mutation could be target for MDS/AML treatment
Scientists have found evidence to suggest that a genetic alteration in osteoblasts can induce acute myeloid leukemia (AML). And this provides a...
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Adding idelalisib improves CLL treatment
The PI3K delta inhibitor idelalisib could turn chronic lymphocytic leukemia (CLL) into a highly treatable disease, according to the lead...
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ACA exchanges limiting for patients with blood cancers, report suggests
Credit: CDC A new report suggests that many health plans in the insurance exchanges mandated by the Affordable Care Act (ACA) will impose high...
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Ponatinib back on the market
Ariad Pharmaceuticals, Inc., has begun shipping the drug to Biologics, Inc., its exclusive specialty pharmacy.
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Case raises questions about BRAF inhibitor’s mechanism
Credit: University of Leicester Results of a case study suggest the BRAF inhibitor vemurafenib does not treat hairy cell leukemia (HCL) in the...
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Histone discovery may have implications for blood cancers
Credit: Eric Smith Investigators have uncovered an unanticipated mechanism underlying trimethylation of a histone that activates gene expression...
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Compound active against a range of cancers
expressing NFAT3c-GFP A little-studied chemical compound has “wide and potent” anticancer activity, investigators have reported in Cancer Cell....
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Group discovers how drugs fight APL
Credit: The Armed Forces Institute of Pathology Results of a new study appear to explain how retinoic acid and arsenic trioxide work against...
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Genetic events drive ALL subtype
a patient with ALL Investigators have identified the genetic events leading to leukemic transformation in ETV6-RUNX1 acute lymphoblastic leukemia...