Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Sleepiest OSA Patients Have Worse CV Outcomes

Publish date:: July 2, 2019

Key clinical point: OSA symptom subtypes are reproducible and associated with cardiovascular risk.

Major finding: Compared with other OSA subtypes, the excessively sleepy group had a more than threefold increased odds of prevalent heart failure, after adjustment for other CV risk factors.

Study details: An analysis of 1,207 patients from the Sleep Heart Study.

Disclosures: Dr. Mazzotti reported having no financial disclosures.

Citation:

Mazzotti D et al. SLEEP 2019, Abstract 0586.

This Week's Must Reads

MDD: Modest improvements in female sexual functioning with adjunctive brexpiprazole,

Transcranial direct current stimulation not clinically relevant in MDD,

Interleukin-1 β and TNF-α hamper antidepressant response in MDD,

Impact of pimavanserin on anxious depression in patients with MDD,

Prior MDD moderates the association between endothelin-1 and post-ACS depressive symptoms,

Must Reads in Sleep Medicine

Study links sleep meds and dementia risk in older adults,

Study validates OSA phenotypes in Latinos,

Insomnia may have a role in generation of stressful life events,

Study confirms link between PAP apnea treatment and dementia onset,

Sleep EEG may predict later antidepressant response,