Key clinical point: Guided Internet-delivered cognitive behavioral treatment (ICBT) significantly improved symptoms after 6 months in adults with major depression who were undergoing routine treatment.

Major finding: About half (48%) of the patients who participated in ICBT showed clinical improvement based on the primary outcome of scores on the Montgomery-Åsberg Depression Rating Scale-Self report (MADRS-S); the average reduction from baseline pre-treatment to the 6-month follow-up visit was 9.65 points.

Study details: The data come from a study of 105 adults assessed between 2015 and 2018.

Disclosures: The study was funded by Norwegian Research Council; the research and implementation of Internet-based treatment for major depressive disorder at Haukeland University Hospital was funded by the Western Norway Regional Health Authority, Directorate of Health, and Haukeland University Hospital. The researchers reported no financial conflicts.