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Obsessive-compulsive personality disorder may involve brain abnormalities
Key clinical point: Obsessive-compulsive personality disorder may involve abnormalities in the hippocampus and amygdala.
Major finding: Hippocampal and amygdalar volume were significantly smaller in patients with obsessive-compulsive personality disorder than in healthy controls.
Study details: The findings are based on comparison of MRI of hippocampal and amygdalar volumes in 16 patients with obsessive-compulsive personality disorder and 18 healthy controls.
Disclosures: The research was funded by Firat University, Elazig, Turkey. The authors reported having no conflicts of interest.
Citation:
Gurok MG et al. J Clin Neurosci. 2019 Apr 5. doi: 10.1016/j.jocn.2019.03.060.