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Lipid profiles distinguish obese and nonobese NAFLD patients

Key clinical point: Lipidomic signatures were distinct between obese and nonobese adults with nonalcoholic fatty liver disease.

Major finding: Lipid metabolites were effective predictors of nonalcoholic fatty liver disease/NASH in nonobese and obese patients (area under the curve, 0.916/0.813 and 0.967/0.812, respectively).

Study details: The data come from a cross-sectional analysis of 295 adults with biopsy-proven nonalcoholic fatty liver disease and 66 healthy controls.

Disclosures: The study was funded by the Korea Basic Science Institute, the Korea Health Industry Department Institute, and the National Research Foundation of Korea. The researchers had no financial conflicts to disclose.

Citation:

Jung Y et al. Aliment Pharmacol Ther. 2020 Sep 6. doi: 10.1111/apt.16066.